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The mannose binding lectin gene influences the severity of chronic liver disease in cystic fibrosis

✍ Scribed by Gabolde, M


Book ID
118020381
Publisher
BMJ Publishing Group
Year
2001
Tongue
English
Weight
163 KB
Volume
38
Category
Article
ISSN
0022-2593

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Mannose-binding lectin (MBL) is a C-type lectin produced mainly by the liver that binds to a wide range of pathogens. Polymorphisms at the promoter and exon 1 of the MBL2 gene are responsible for low serum levels of MBL and have been associated with an increased risk of infections. We prospectively