George Albert Eduard Brutus Gilles de la Tourette, a 28-yearqld student of Charcot, first characterized the tic disorder named after him 100 years ago (1). In his original nine cases, he pointed out that besides motor tics, seen in all patients, other peculiar symptoms were present. These included i
The management of tics
β Scribed by David Shprecher; Roger Kurlan
- Publisher
- John Wiley and Sons
- Year
- 2008
- Tongue
- English
- Weight
- 99 KB
- Volume
- 24
- Category
- Article
- ISSN
- 0885-3185
No coin nor oath required. For personal study only.
β¦ Synopsis
Abstract
A tic is a stereotyped repetitive involuntary movement or sound, frequently preceded by premonitory sensations or urges. Most tic disorders are genetic or idiopathic in nature, possibly due to a developmental failure of inhibitory function within frontalβsubcortical circuits modulating volitional movements. Currently available oral medications can reduce the severity of tics, but rarely eliminate them. Botulinum toxin injections can be effective if there are a few particularly disabling motor tics. Deep brain stimulation has been reported to be an effective treatment for the most severe cases, but remains unproven. A comprehensive evaluation accounting for secondary causes, psychosocial factors, and comorbid neuropsychiatric conditions is essential to successful treatment of tic disorders. Β© 2008 Movement Disorder Society
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## Abstract Botulinum toxin (BTX) injections provide effective treatment for a variety of disorders manifested by inappropriate muscle contractions, but its efficacy in the treatment of tics has not been previously studied. Ten male patients 13β53 years of age who were diagnosed with Tourette's syn