๐”– Bobbio Scriptorium
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The Mammalian Y Chromosome


Publisher
Springer US
Year
1990
Tongue
English
Weight
17 KB
Volume
20
Category
Article
ISSN
0001-8244

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The mammalian Y chromosome: a new perspe
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For several decades, the mammalian Y chromosome was considered a genetic "desert," with the testis determinant being the sole survivor of the attrition that followed the chromosome's inception. Aside from the addition of a genetic factor required for spermatogenesis to the human Y chromosome in 1976

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In mammals, male sex determination, as well as spermatogenesis, is controlled by genes on the Y chromosome. Evolutionary comparisons may be used to detect and test candidate genes for these functions, under the hypothesis that the rapid evolution of the mammalian Y chromosome causes it to contain fe

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None of the up to now localized and expressed oncogenes maps to the mammalian X chromosome. This fact is discussed in the light of a trans-acting regulation mechanism for oncogenes. Such a specific regulation mechanism is demonstrated here for a qualitative change--i.e., varying timing of DNA-replic