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The malignant potential of a succinate dehydrogenase subunit B germline mutation

✍ Scribed by Fuentes Gómez, C.; Menéndez, E.; Pineda, J.; Martínez De Esteban, J. P.; Anda, E.; Goñi, M. J.; Bausch, B.; Neumann, H. P. H.

Book ID
125335008
Publisher
Springer-Verlag
Year
2006
Tongue
English
Weight
192 KB
Volume
29
Category
Article
ISSN
0391-4097

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## Abstract ## Background Paragangliomas of the head and neck are rare, mostly benign tumors. Approximately 10% to 15% of paragangliomas are caused by mutations in the succinate dehydrogenase (SDH) genes B, C, or D. These are often multifocal as part of paraganglioma syndromes and hormone secretin