𝔖 Bobbio Scriptorium
✦   LIBER   ✦

The major histocompatibility complex — progress and perspectives

✍ Scribed by Narinder Mehra

Publisher
Elsevier Science
Year
1998
Tongue
English
Weight
256 KB
Volume
19
Category
Article
ISSN
0167-5699

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✦ Synopsis

DRB1 and HLA-DQB1 was observed in infertile women possessing the spermimmobilizing antibodies in their sera.

As regards male infertility, Fas ligand, expressed on the surface of Sertoli cells, is implicated in preventing activated lymphocytes from infiltrating the testis: breakdown in this immune privilege may lead to infertility. Other discussion will focus on the role of intercellular adhesion molecule I (ICAM-1) and leukocyte function-associated molecule I (LFA-1) in autoimmune orchitis.

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Major histocompatibility complex, t-comp
Major histocompatibility complex, t-complex, and leukemia
✍ M. Tevfik Dorak; Alan K. Burnett 📂 Article 📅 1992 🏛 Springer Netherlands 🌐 English ⚖ 941 KB

In experimental models, leukemia was the first disease shown to have an association with the major histocompatibility complex (MHC) genes. In humans, several allelic human-leukocyte antigen (HLA) associations also have been recognized. In addition to allelic associations, atypical HLA segregation pa