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The Low-dose Ionizing Radiation Stimulates Cell Proliferation via Activation of the MAPK/ERK Pathway in Rat Cultured Mesenchymal Stem Cells

✍ Scribed by LIANG, Xinyue; SO, You Ho; CUI, Jiuwei; MA, Kewei; XU, Xiaoyi; ZHAO, Yuguang; CAI, Lu; LI, Wei

Book ID: 121834637
Publisher: Japan Science and Technology Information Aggregator, Electronic
Year: 2011
Tongue: English
Weight: 413 KB
Volume: 52
Category: Article
ISSN: 0449-3060
DOI: 10.1269/jrr.10121

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## Abstract Blood vessel injury results in limited oxygen tension and diffusion leading to hypoxia, increased anaerobic metabolism, and elevated production of acidic metabolites that cannot be easily removed due to the reduced blood flow. Therefore, an acidic extracellular pH occurs in the local mi