The low-density lipoprotein (LDL) receptor genes from 18 unrelated Japanese heterozygotes and 1 homozygote with classical familial hypercholesterolemia were analyzed by Southern blot hybridization using fragments of the human LDL receptor cDNA as probes. Four different deletion mutations were detect
โฆ LIBER โฆ
The low-density lipoprotein receptor gene family: multiple roles in lipid metabolism
โ Scribed by Thomas E. Willnow
- Publisher
- Springer
- Year
- 1999
- Tongue
- English
- Weight
- 114 KB
- Volume
- 77
- Category
- Article
- ISSN
- 0946-2716
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Familial hypercholesterolemia (FH) is a common autosomal dominant disorder of lipid metabolism caused by mutations