𝔖 Bobbio Scriptorium
✦   LIBER   ✦

The Loop 5 Element Structurally and Kinetically Coordinates Dimers of the Human Kinesin-5, Eg5

✍ Scribed by Waitzman, Joshua S.; Larson, Adam G.; Cochran, Jared C.; Naber, Nariman; Cooke, Roger; Kull, F. Jon; Pate, Edward; Rice, Sarah E.


Book ID
119209200
Publisher
Biophysical Society
Year
2011
Tongue
English
Weight
812 KB
Volume
101
Category
Article
ISSN
0006-3495

No coin nor oath required. For personal study only.


📜 SIMILAR VOLUMES


X-Ray Structure, Conformational Analysis
✍ C.Oliver Kappe; Oleg V Shishkin; Georg Uray; Petra Verdino 📂 Article 📅 2000 🏛 Elsevier Science 🌐 French ⚖ 108 KB

The conformational features of the mitotic kinesin Eg5 inhibitor monastrol were investigated by computational (AM1, HF/3-21G ‫ء‬ ), X-ray diffraction, and NMR studies showing that monastrol is a conformationally highly flexible molecule. Racemic monastrol was resolved by direct enantioselective HPLC