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The long-term suppressive effect of prior activation of synaptic inputs by low-frequency stimulation on induction of long-term potentiation in CA1 neurons of guinea pig hippocampal slices

✍ Scribed by Fujii Satoshi; Kuroda Yoichiro; Miura Masami; Furuse Hidekazu; Sasaki Hiroshi; Kaneko Kenya; Ito Kenichi; Chen Zhixiong; Kato Hiroshi


Publisher
Springer-Verlag
Year
1996
Tongue
English
Weight
773 KB
Volume
111
Category
Article
ISSN
0014-4819

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Long-term potentiation (LTP) is a long-lasting increase in synaptic strength induced by high frequency stimulation. LTP may participate in learning and memory formation. In many synaptic systems, LTP is dependent on intact function of N-methyl-D-aspartate (NMDA) receptors. NMDA receptors may be inhi