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The long ascending monoaminergic neuromediator systems in senile dementia of the Alzheimer type (SDAT): Neuropathological and neurochemical findings

✍ Scribed by G. Moll; K. Jellinger; P. Riederer


Publisher
Springer
Year
1989
Tongue
English
Weight
62 KB
Volume
1
Category
Article
ISSN
1435-1463

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✍ Albert Wettstein; RenΓ© Spiegel πŸ“‚ Article πŸ“… 1984 πŸ› Springer 🌐 English βš– 216 KB

The muscarinic agonist RS 86 was administered to patients with Alzheimer's disease (AD) and senile dementia of the Alzheimer type (SDAT) in a series of controlled clinical trials. Daily doses were up to 3.0 mg orally for a maximum duration of 18 weeks. RS 86 produced typical peripheral cholinergic e