## Abstract Using a yeast twoโhybrid library screen, we have identified that the heart specific FHL2 protein, fourโandโaโhalf LIM protein 2, interacted with human DNAโbinding nuclear protein, hNP220. Domain studies by the yeast twoโhybrid interaction assay revealed that the second LIM domain togeth
The LIM motif: A specific zinc-binding protein domain
โ Scribed by D.R. Winge; J.W. Michelsen; J.L. Kosa; K.L. Schmeichel; M.C. Beckerle
- Publisher
- Elsevier Science
- Year
- 1993
- Tongue
- English
- Weight
- 73 KB
- Volume
- 51
- Category
- Article
- ISSN
- 0162-0134
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## Abstract A peptide corresponding to the three zinc finger domains of the human transcription factor Sp1 has been expressed and found to bind a consensus Sp1 binding site with the sequence 5โฒโGGGGCGGGGโ3โฒ. Examination of the amino acid distributions within a large zinc finger sequence data base a