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The ligandin (non-substrate) binding site of human pi class glutathione transferase is located in the electrophile binding site (H-site)

✍ Scribed by Aaron J Oakley; Mario Lo Bello; Marzia Nuccetelli; Anna P Mazzetti; Michael W Parker


Book ID
115629560
Publisher
Elsevier Science
Year
1999
Tongue
English
Weight
511 KB
Volume
291
Category
Article
ISSN
0022-2836

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πŸ“œ SIMILAR VOLUMES


Implications of the ligandin binding sit
✍ Zeyad Yassin; Emilia Ortiz-SalmerΓ³n; Federico Garcı́a-Maroto; Carmen BarΓ³n; Luis πŸ“‚ Article πŸ“… 2004 πŸ› Elsevier Science 🌐 English βš– 532 KB

The binding interactions between dimeric glutathione transferase from Schistosoma japonicum (Sj26GST) and bromosulfophthalein (BS) or 8-anilino-1-naphthalene sulfonate (ANS) were characterised by fluorescence spectroscopy and isothermal titration calorimetry (ITC). Both ligands inhibit the enzymatic