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The ligand-selectivity of cloned human and rat opiate mu receptors studied with [125I]IOXY-AGO

✍ Scribed by Richard B. Rothman; Heng Xu; Jia Bel Wang; John S. Partilla; Hiroshi Kayakiri; Kenner C. Rice; George R. Uhl


Book ID
119118663
Publisher
Elsevier Science
Year
1994
Tongue
English
Weight
129 KB
Volume
54
Category
Article
ISSN
0167-0115

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Ligand selectivity of cloned human and r
✍ Richard B. Rothman; Heng Xu; Jia Bei Wang; John S. Partilla; Hiroshi Kayakiri; K πŸ“‚ Article πŸ“… 1995 πŸ› John Wiley and Sons 🌐 English βš– 513 KB

Opiate receptors play major roles in analgesic and euphoric effects of opiate drugs. Recent cloning of cDNAs encoding the rodent and human p receptor revealed high homology between the predicted receptors but also some sequence differences. To determine if these sequence differences produced signifi