The Lewis acid mediated reaction of carbamates with ?-oxygenated allyltin and its application to (�)-statine synthesis
✍ Scribed by Yamamoto, Yoshinori; Schmid, Martin
- Book ID
- 120643050
- Publisher
- The Royal Society of Chemistry
- Year
- 1989
- Tongue
- English
- Weight
- 241 KB
- Volume
- 18
- Category
- Article
- ISSN
- 0022-4936
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Taking the judicious choice of the Lewis acid employed, the glyoxylate ene reactions are shown to proceed with a high level of either erythro or threo diastereoselection. The utility of the ene methodology is demonstrated through the stereocontrolled synthesis of a 22F&hydroxy-23-carboxylate steroid