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The Lewis acid-catalyzed [3+1+1] cycloaddition of azomethine ylides with isocyanides

✍ Scribed by Soeta, Takahiro; Miyamoto, Yoshiaki; Fujinami, Shuhei; Ukaji, Yutaka


Book ID
125819252
Publisher
Elsevier Science
Year
2014
Tongue
French
Weight
604 KB
Volume
70
Category
Article
ISSN
0040-4020

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✍ Pandiancherri, Shveta; Ryan, Sarah J.; Lupton, David W. πŸ“‚ Article πŸ“… 2012 πŸ› Royal Society of Chemistry 🌐 English βš– 635 KB

Lewis base catalysed 1,3-dipolar cycloaddition between Ξ±,Ξ²-unsaturated acyl fluorides and N-[(trimethylsilyl)methyl]amino ethers has been achieved using 1 mol% DMAP. Competition experiments and (19)F-NMR studies indicate that the cycloaddition occurs preferentially between the Ξ±,Ξ²-unsaturated acyl f