Metabolic studies in a case of Lesch-Nyhan syndrome are presented. De novo synthesis of purine was shown to be inhibited upon adenine administration. The excretion of oxypurines is elevated, however, by an increased incorporation of the administered adenine into purine bases. A side effect of adenin
β¦ LIBER β¦
THE LESCH-NYHAN SYNDROME
β Scribed by William L. Nyhan
- Book ID
- 115263713
- Publisher
- John Wiley and Sons
- Year
- 2008
- Tongue
- English
- Weight
- 437 KB
- Volume
- 20
- Category
- Article
- ISSN
- 0012-1622
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