## Abstract ## Objective Findings of recent in vivo and in vitro studies suggest that oxidized lowโdensity lipoprotein (oxโLDL) plays a role in the degeneration of cartilage. The purpose of this study was to determine whether oxโLDL induces chondrocyte senescence through binding to lectinโlike oxโ
The lectin-like oxidized low-density lipoprotein receptor and its role in atherosclerosis
โ Scribed by Mehmet Cilingiroglu; Kerem Ozer
- Book ID
- 107533892
- Publisher
- Current Science Inc.
- Year
- 2005
- Tongue
- English
- Weight
- 156 KB
- Volume
- 7
- Category
- Article
- ISSN
- 1523-3804
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๐ SIMILAR VOLUMES
Lipoprotein oxidation is involved in the genesis of atherosclerosis. In chronic renal failure (CRF), oxidative stress is enhanced because of an imbalance between pro-oxidant and antioxidant systems. Oxidative modifications of low-density lipoproteins (LDLs) occur not only at the level of lipid moiet
## Abstract ## Objective To investigate for the presence of oxidized lowโdensity lipoprotein (oxโLDL) and lectinโlike oxidized LDL receptor 1 (LOXโ1) in cartilage specimens from rheumatoid arthritis (RA) joints and to determine whether the interaction of oxโLDL with LOXโ1 can induce matrix metallo