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The late effect of 7-oxo prostacyclin protects the rat heart against calcium paradox

✍ Scribed by Tatiana Ravingerová; Narcisa Tribulová; Attila Ziegelhöffer

Book ID
118346334
Publisher
Elsevier Science
Year
1993
Tongue
English
Weight
825 KB
Volume
53
Category
Article
ISSN
0024-3205

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Prevention by 7-oxo-prostacyclin of the
Prevention by 7-oxo-prostacyclin of the calcium paradox in rat heart: Role of the sarcolemmal (Na,K)-ATPase
✍ Attila Ziegelhöffer; Tatiana Ravingerová; Andrej Džurba; Narcisa Tribulová; Jan 📂 Article 📅 1996 🏛 Springer 🌐 English ⚖ 711 KB

It is demonstrated a fast and significant depression in the sarcolemmal (Na,K)-ATPase activity that occurs as early as 25 sec after the onset of Ca2+ depletion, and participates in the development of Ca(2+)-paradox in the rat heart. Pretreatment of the animals with 7-oxo-prostacyclin (PGI2) 24-48 h