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The lactose permease of Escherichia coli: overall structure, the sugar-binding site and the alternating access model for transport

✍ Scribed by Jeff Abramson; Irina Smirnova; Vladimir Kasho; Gillian Verner; So Iwata; H.Ronald Kaback


Book ID
117105876
Publisher
Elsevier Science
Year
2003
Tongue
English
Weight
320 KB
Volume
555
Category
Article
ISSN
0014-5793

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Ligand-Induced conformational changes in
✍ Jianhua Wu; Stathis Frillingos; John Voss; H. Ronald Kaback πŸ“‚ Article πŸ“… 1994 πŸ› Cold Spring Harbor Laboratory Press 🌐 English βš– 848 KB

## Abstract By using a lactose permease mutant containing a single Cys residue in place of Val 331 (helix X), conformational changes induced by ligand binding were studied. With right‐side‐out membrane vesicles containing Val 331 β†’ Cys permease, lactose transport is inactivated by either __N__‐ethy