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The Kinetics, Function, and Regulation of P-Selectin Expressed by Human Brain Microvessel Endothelial Cells in Primary Culture

✍ Scribed by Alexander S. Easton; Katerina Dorovini-Zis

Book ID
115641225
Publisher
Elsevier Science
Year
2001
Tongue
English
Weight
597 KB
Volume
62
Category
Article
ISSN
0026-2862

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## Abstract A major concern regarding the chronic administration of antiretroviral drugs is the potential for induction of drug efflux transporter expression (i.e., P‐glycoprotein, P‐gp) at tissue sites that can significantly affect drug distribution and treatment efficacy. Previous data have shown