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The kinetic mechanism of human placental aldose reductase and aldehyde reductase II

โœ Scribed by Aruni Bhatnagar; Ballabh Das; Sandhya R. Gavva; Paul F. Cook; Satish K. Srivastava


Book ID
115707810
Publisher
Elsevier Science
Year
1988
Tongue
English
Weight
788 KB
Volume
261
Category
Article
ISSN
0003-9861

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Aldose reductase (AR) catalyzes the NADPH-dependent reduction of glucose and other sugars to their respective sugar alcohols. The NADP + /NADPH exchange is the rate-limiting step for this enzyme and contributes in varying degrees to the catalytic rates of other aldo-keto reductase superfamily enzyme