The Kinesin-1 Tail Binds to Microtubules in a Manner Similar to Tau
β Scribed by Seeger, Mark; Rice, Sarah
- Book ID
- 122614044
- Publisher
- Biophysical Society
- Year
- 2010
- Tongue
- English
- Weight
- 33 KB
- Volume
- 98
- Category
- Article
- ISSN
- 0006-3495
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π SIMILAR VOLUMES
Previous studies have demonstrated that the microtubule-associated proteins MAP-2 and tau interact selectively with common binding domains on tubulin defined by the low-homology segments alpha (430-441) and beta (422-434). It has been also indicated that the synthetic peptide VRSKIGSTENLKHQPGGG corr
Treatment of proteins in vitro with sulfhydryl (SH)-reactive compounds has been used successfully to determine protein regions critical for normal function. To probe structure-function relationships in the microtubule (MT) motor kinesin, the motor was treated with two SH reactive compounds, n-ethylm