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The KH module has an αβ fold

✍ Scribed by Maria Antonietta Castiglione Morelli; Gunter Stier; Toby Gibson; Catherine Joseph; Giovanna Musco; Annalisa Pastore; Gilles Travè


Book ID
115929821
Publisher
Elsevier Science
Year
1995
Tongue
English
Weight
469 KB
Volume
358
Category
Article
ISSN
0014-5793

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✍ Franca Fraternali; Pietro Amodeo; Giovanna Musco; Michael Nilges; Annalisa Pasto 📂 Article 📅 1999 🏛 John Wiley and Sons 🌐 English ⚖ 944 KB

The K-homology (KH) module is a novel RNA-binding motif. The structures of a representative KH motif from vigilin (vig-KH6) and of the first KH domain of fmr1 have been recently solved by nuclear magnetic resonance (NMR) and automated assignment-refinement techniques (ARIA). While a hydrophobic resi