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The key role of residue 5 in angiotensin II

✍ Scribed by Serge Fermandjian; Constantin Sakarellos; Françlois Piriou; Michel Juy; Flavio Toma; Hung Lam Thanh; Karl Lintner; Mahesh C. Khosla; Robert R. Smeby; F. Merlin Bumpus

Publisher: Wiley (John Wiley & Sons)
Year: 1983
Tongue: English
Weight: 254 KB
Volume: 22
Category: Article
ISSN: 0006-3525
DOI: 10.1002/bip.360220131

No coin nor oath required. For personal study only.

✦ Synopsis

The conformation-biological activity relationships in a series of angiotensin I1 analogs substituted in position 5 were studied. Results indicated that only analogs with &branched residue in position 5 possess spectral and biological properties identical to that of parent angiotensin 11.

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