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The kappa-opioid receptor is upregulated in the spinal cord and locus ceruleus but downregulated in the dorsal root ganglia of morphine tolerant rats

✍ Scribed by Xuan-ying Li; Li Sun; Jie He; Zhao-li Chen; Fang Zhou; Xiao-yan Liu; Ruo-shan Liu


Book ID
113504881
Publisher
Elsevier Science
Year
2010
Tongue
English
Weight
930 KB
Volume
1326
Category
Article
ISSN
0006-8993

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## Abstract To assess the validity of rodent models for investigating the role of delta opioid receptors (DOR) in analgesia, the distribution of DOR binding and mRNA were compared between rodent and primate spinal cord and dorsal root ganglia (DRG), using receptor autoradiography and in situ hybrid