The kallikrein-kininogen-kinin system
β Scribed by Marion E. Webster
- Publisher
- John Wiley and Sons
- Year
- 1966
- Tongue
- English
- Weight
- 724 KB
- Volume
- 9
- Category
- Article
- ISSN
- 0004-3591
No coin nor oath required. For personal study only.
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Tissue kallikrein cleaves kininogens to release kinins. Kinins mediate inflammation by activating constitutive bradykinin receptor-2 (BR2), which are rapidly desensitized, and induced by inflammatory cytokines bradykinin receptor-1 (BR1), resistant to desensitization. Intestinal tissue kallikrein (
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