The Juxtaglomerular Apparatus: Structure and Function

✍ Scribed by Prof. Dr. med. Roland Taugner, Prof. Dr. med. Eberhard Hackenthal (auth.)

• Publisher: Springer-Verlag Berlin Heidelberg
• Year: 1989
• Tongue: English
• Leaves: 308
• Edition: 1
• Category: Library

✦ Synopsis

Knowledge of the juxtaglomerular apparatus (JGA) of the kidney and of the synthesis and secretion of renin has increased to such an extent over the past few years that it is now appropriate to summarize this knowledge in a monograph on the JGA, the first of its kind. It was the authors' special concern to demonstrate the association between structure and function for renin secretion, not only within the juxtaglomerular region, but also in the region of the renal cortex beyond the JGA. The description of the pathology of the human JGA, studded with references to experimental findings but nevertheless fully self-contained, should help to make this monograph also useful for clinicians.

✦ Table of Contents

Front Matter....Pages I-X
The Juxtaglomerular Apparatus — History of a Concept....Pages 1-3
Morphology of the Juxtaglomerular Apparatus....Pages 5-43
Elements with Structural and/or Functional Relationships to the Juxtaglomerular Apparatus....Pages 45-67
Intrarenal Distribution of the Different Components of the Renin-Angiotensin System....Pages 69-101
Synthesis and Traffic of Renin in Epithelioid Cells....Pages 103-126
Morphology of Renin Release from Epithelioid Cells....Pages 127-136
Physiology, Pathophysiology, and Biochemistry of Renin Secretion....Pages 137-193
Electrophysiology of Epithelioid Cells....Pages 195-196
Intrarenal Renin-Angiotensin System....Pages 197-214
Metaplastic Transformation Between Smooth Muscle Cells and Epithelioid Cells....Pages 215-219
Long-term Modulation of Renin Synthesis and Secretion....Pages 221-224
Interspecies Variations of the Juxtaglomerular Apparatus in Mammals....Pages 225-230
Phylogeny and Ontogeny of the Juxtaglomerular Apparatus....Pages 231-239
Pathology of the Human Juxtaglomerular Apparatus....Pages 241-254
Back Matter....Pages 255-306

✦ Subjects

Nephrology; Human Physiology; Pathology