The c-Jun NH(2)-terminal kinases (JNKs) are an evolutionarily conserved sub-group of mitogen-activated protein (MAP) kinases. Recent studies have improved our understanding of the physiological function of the JNK pathway. Roles of novel molecules that participate in the JNK pathway have been define
β¦ LIBER β¦
The JNK signal transduction pathway
β Scribed by Claire R Weston; Roger J Davis
- Book ID
- 113524853
- Publisher
- Elsevier Science
- Year
- 2007
- Tongue
- English
- Weight
- 293 KB
- Volume
- 19
- Category
- Article
- ISSN
- 0955-0674
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## Abstract Recently, acute total glucose deprivation has been shown to cause activation of ASK1βMEKβMAPK signal transduction and dissociation of glutaredoxin (GRX) from apoptosis signalβregulating kinase 1 (ASK1). In this study, we investigated whether clinically relevant concentrations (0.01β0.1