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The JAK2 V617F Mutation in Pediatric Myeloproliferative Neoplasms: How and When?

✍ Scribed by Langabeer, Stephen E.; Smith, Owen P.; McMahon, Corrina

Book ID
126873552
Publisher
Informa plc
Year
2014
Tongue
English
Weight
76 KB
Volume
31
Category
Article
ISSN
0888-0018

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The V617F JAK2 mutation and the myelopro
The V617F JAK2 mutation and the myeloproliferative disorders
✍ Melanie J Percy; Mary Frances McMullin πŸ“‚ Article πŸ“… 2005 πŸ› John Wiley and Sons 🌐 English βš– 70 KB

## Abstract The discovery this year of a single mutation in the Janus Kinase (__JAK__)‐2 gene in a high percentage of cases of polycythaemia vera (PV), essential thrombocythaemia (ET) and myelofibrosis suggests that it maybe the underlying molecular mechanism for these disorders. Different approach