The JmjC domain protein Epe1 prevents un
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Trewick, Sarah C; Minc, Elsa; Antonelli, Richard; Urano, Takeshi; Allshire, Robi
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Article
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2007
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Nature Publishing Group
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English
⚖ 420 KB
Heterochromatin normally has prescribed chromosomal positions and must not encroach on adjacent regions. We demonstrate that the fission yeast protein Epe1 stabilises silent chromatin, preventing the oscillation of heterochromatin domains. Epe1 loss leads to two contrasting phenotypes: alleviation o