A design approach to the structural anal
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T. L. Ciardelli; B. Landgraf; R. Gadski; J. Strnad; F. E. Cohen; K. A. Smith
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Article
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1988
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John Wiley and Sons
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English
โ 610 KB
A semi-synthetic protein design approach has been employed for the structural investigation of a putative helical region at the C-terminus of Interleukin-2. With crystallographic or NMR derived conformational data as yet unavailable, we have relied only on primary sequence information and computer-a