The effect of rheumatoid factor (RF) on complement-activating capacity of aggregated IgG was investigated. The degree of complement activation induced by the addition of specific amounts of aggregated IgG to patients' sera and normal sera was demonstrated by the inhibition of hemolytic activity (%IH
β¦ LIBER β¦
The isolation of immune complexes containing IgM rheumatoid factor and recovery of IgG rheumatoid factor from the complexes
β Scribed by Valerie E. Jones; Pamela J. Cowley; Christine Allen; C.J. Elson
- Book ID
- 118898009
- Publisher
- Elsevier Science
- Year
- 1980
- Tongue
- English
- Weight
- 731 KB
- Volume
- 37
- Category
- Article
- ISSN
- 0022-1759
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## Abstract Sera from 10 patients with juvenile arthritis (JA), 2 seropositive and 8 with hidden rheumatoid factor (RF), were subjected to affinity chromatography on a rabbit antiβhuman IgM column. Material retained by the column was eluted sequentially by 1__M__ NH~3~ and 0.1__M__ glycineβHCl buff
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