✦ LIBER ✦

The isolation and use of a benzodiazepine iminochloride for the efficient construction of flumazenil

✍ Scribed by Mark Rogers-Evans; Paul Spurr; Michael Hennig

Book ID: 104253018
Publisher: Elsevier Science
Year: 2003
Tongue: French
Weight: 179 KB
Volume: 44
Category: Article
ISSN: 0040-4039
DOI: 10.1016/s0040-4039(03)00078-9

No coin nor oath required. For personal study only.

✦ Synopsis

The benzodiazepine iminochloride 2 has been isolated, characterized and its reaction with a glycinate enolate synthon investigated resulting in an efficient synthesis of the imidazobenzodiazepine flumazenil.

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