The ISG15/USP18 ubiquitin-like pathway (ISGylation system) in Hepatitis C Virus infection and resistance to interferon therapy
โ Scribed by Limin Chen; Shilin Li; Ian McGilvray
- Book ID
- 116308090
- Publisher
- Elsevier Science
- Year
- 2011
- Tongue
- English
- Weight
- 479 KB
- Volume
- 43
- Category
- Article
- ISSN
- 1357-2725
No coin nor oath required. For personal study only.
๐ SIMILAR VOLUMES
A region associated with sensitivity to interferon (IFN) has been identified previously in the nonstructural protein 5A (NS5A) of hepatitis C virus (HCV) genotype 1b. A study was undertaken to determine whether the presence of mutations in the NS5A 2209-2248 sequence could serve as a predictor of re
Combination treatment with pegylated-interferon-alpha (PEG IFN-โฃ) and ribavirin, the current recommended therapy for chronic hepatitis C virus (HCV) infection, results in a sustained virological response (SVR) in only about half of patients. Because genes involved in the interferon-alpha pathway may