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The Inwardly Rectifying Potassium Channel Kir1.1: Development of Functional Assays to Identify and Characterize Channel Inhibitors

✍ Scribed by Felix, John P.; Priest, Birgit T.; Solly, Kelli; Bailey, Timothy; Brochu, Richard M.; Liu, Chou J.; Kohler, Martin G.; Kiss, Laszlo; Alonso-Galicia, Magdalena; Tang, Haifeng; Pasternak, Alexander; Kaczorowski, Gregory J.; Garcia, Maria L.


Book ID
120974871
Publisher
Mary Ann Liebert
Year
2012
Tongue
English
Weight
1015 KB
Volume
10
Category
Article
ISSN
1540-658X

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## Abstract Dystroglycan (DG) is part of a multiprotein complex that links the extracellular matrix to the actin cytoskeleton of muscle fibers and that is involved in aggregating acetylcholine receptors at the neuromuscular junction. This complex is also expressed in regions of the central nervous