✦ LIBER ✦

The involvement of μ- and κ- but not δ-opioid receptors in the body weight gain of suckling rats

✍ Scribed by H. C. Jackson; R. D. E. Sewell

Publisher: Springer
Year: 1984
Tongue: English
Weight: 174 KB
Volume: 84
Category: Article
ISSN: 0033-3158
DOI: 10.1007/bf00432046

No coin nor oath required. For personal study only.

✦ Synopsis

The effects of the benzomorphan antagonist Mr 2266 and the selective g-antagonist ICI 154,129 on the body weight gain of 6-day-old suckling rat pups was observed. Mr 2266 significantly reduced body weight gain in these animals, though ICI 154,129 had no affect on this variable. These findings suggest that ~t-and K-but probably not g-opioid receptors are involved in the regulation of ingestive behaviours in infant rats. The results are discussed in relation to the development of opioid-receptor subtypes in the neonatal rat brain.

📜 SIMILAR VOLUMES

Blockade of dopamine receptors reverses

Blockade of dopamine receptors reverses the behavioral effects of endogenous enkephalins in theNucleus caudatusbut not in theNucleus accumbens: differential involvement of δ and μ opioid receptors

✍ V. Daugé; P. Rossignol; B. P. Roques 📂 Article 📅 1989 🏛 Springer 🌐 English ⚖ 965 KB

Major difference in the expression of δ-

Major difference in the expression of δ- and μ-opioid receptors between turtle and rat brain

✍ Ying Xia; Gabriel G. Haddad 📂 Article 📅 2001 🏛 John Wiley and Sons 🌐 English ⚖ 416 KB

Opioid peptide receptor studies, 11: Inv

Opioid peptide receptor studies, 11: Involvement of Tyr148, Trp318 and His319 of the rat μ-opioid receptor in binding of μ-selective ligands

✍ Heng Xu; Yi-Feng Lu; John S. Partilla; Qiao-Xi Zheng; Jia-Bei Wang; George A. Br 📂 Article 📅 1999 🏛 John Wiley and Sons 🌐 English ⚖ 135 KB 👁 1 views

Previous data obtained with the cloned rat µ opioid receptor demonstrated that the ''super-potent'' opiates, ohmefentanyl (RTI-4614-4) and its four enantiomers, differ in binding affinity, potency, efficacy, and intrinsic efficacy. Molecular modeling (Tang et al., 1996) of fentanyl derivatives bindi

Effects of intracerebroventricular injec

Effects of intracerebroventricular injection of opioid peptides selective for μ, δ and κ receptors on discriminative stimulus properties of pentazocine in the rat

✍ Makoto Ukai; Eiji Mori; Tsutomu Kameyama 📂 Article 📅 1998 🏛 John Wiley and Sons 🌐 English ⚖ 131 KB 👁 1 views

The present study was designed to investigate the eects of centrally administered morphine and opioid peptides on the discriminative stimulus properties of pentazocine in the rat. Rats were trained to discriminate 3 mg/kg (s.c.) of pentazocine from vehicle in a shock avoidance paradigm. A 3 mg/kg (s