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The involvement of reactive oxygen species (ROS) and p38 mitogen-activated protein (MAP) kinase in TRAIL/Apo2L-induced apoptosis

✍ Scribed by Myoung-Woo Lee; Soon Cheol Park; Young Geun Yang; Soon Ock Yim; Hee Sun Chae; Jae-Hyung Bach; Hyun Jung Lee; Kyung Yong Kim; Won Bok Lee; Sung Su Kim


Book ID
117103843
Publisher
Elsevier Science
Year
2002
Tongue
English
Weight
345 KB
Volume
512
Category
Article
ISSN
0014-5793

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## Abstract Our previous study showed that cobalt chloride (CoCl~2~) could induce PC12 cell apoptosis and that the CoCl~2~‐treated PC12 cells may serve as a simple in vitro model for the study of the mechanism of hypoxia‐linked neuronal disorders. The aim of this study is to elucidate the mechanism