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The involvement of osteopontin and its receptors in multiple myeloma cell survival, migration and invasion in the murine 5T33MM model

✍ Scribed by Jo Caers; Ursula Günthert; Hendrik De Raeve; Els Van Valckenborgh; Eline Menu; Ivan Van Riet; Benjamin Van Camp; Karin Vanderkerken

Book ID: 108673562
Publisher: John Wiley and Sons
Year: 2005
Tongue: English
Weight: 239 KB
Volume: 0
Category: Article
ISSN: 0007-1048
DOI: 10.1111/j.1365-2141.2005.05886.x

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## Abstract During the last decade, a central role for insulin‐like growth factor 1 (IGF‐1) in the pathophysiology of multiple myeloma (MM) has been well established. IGF‐I provided by the tumor–microenvironment interaction may directly and indirectly facilitate the migration, survival and expansio