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The involvement of Gab1 and PI 3-kinase in β1 integrin signaling in keratinocytes

✍ Scribed by Yoshihiro Kuwano; Manabu Fujimoto; Rei Watanabe; Nobuko Ishiura; Hiroko Nakashima; Mayumi Komine; Tatsuo S. Hamazaki; Kunihiko Tamaki; Hitoshi Okochi

Book ID
116295326
Publisher
Elsevier Science
Year
2007
Tongue
English
Weight
389 KB
Volume
361
Category
Article
ISSN
0006-291X

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## Abstract βig‐h3 is an extracellular matrix (ECM) protein whose expression is highly induced by transforming growth factor beta1 (TGF‐β1). We previously demonstrated that βig‐h3 has two α3β1 integrin‐interacting motifs, which promote adhesion, migration, and proliferation of human keratinocytes.