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The involvement of cytoskeleton in the regulation of transbilayer movement of phospholipids in human blood platelets

โœ Scribed by Paul Comfurius; Edouard M. Bevers; Robert F.A. Zwaal

Book ID
115727326
Publisher
Elsevier Science
Year
1985
Tongue
English
Weight
753 KB
Volume
815
Category
Article
ISSN
0005-2736

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The involvement of the cytoskeleton in r
The involvement of the cytoskeleton in regulating IP3 receptor-mediated internal Ca2+ release in human blood platelets.
โœ Lilly Y.W. Bourguignon; Naoko Iida; Hengtao Jin ๐Ÿ“‚ Article ๐Ÿ“… 1993 ๐Ÿ› Elsevier Science ๐ŸŒ English โš– 468 KB

## Abstract In this study we have used saponin to permeabilize platelet membranes in order to test directly the involvement of IP~3~ in regulating internal Ca^2+^ release, and to measure IP~3~ binding to its receptor. Our results indicate that platelet vesicles release Ca^2+^ as early as 3 seconds