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The (In)Validity of sensitivity and specificity

✍ Scribed by Irene Guggenmoos-Holzmann; Hans C. van Houwelingen

Publisher
John Wiley and Sons
Year
2000
Tongue
English
Weight
112 KB
Volume
19
Category
Article
ISSN
0277-6715

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✦ Synopsis

This paper is a legacy of the "rst author, and after her untimely death reconstructed by the second author as a tribute to Irene Guggenmoos's contribution to biostatistics. It discusses two di!erent views on diagnostic testing: the classical view in which sensitivity and speci"city of a diagnostic test are considered universal constants, and the more statistical point of view that focuses on predictive values. The di!erences between the two paradigms are outlined and practical examples are discussed to show that the familiar concepts of sensitivity and speci"city must be handled with care and not used indiscriminately.

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