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The introduction of nitrile-groups into heterocycles and conversion of carboxylic groups into their corresponding nitriles with chlorosulfonylisocyanate and triethylamine

✍ Scribed by Helmut Vorbrüggen; Konrad Krolikiewicz


Book ID
108372284
Publisher
Elsevier Science
Year
1994
Tongue
French
Weight
780 KB
Volume
50
Category
Article
ISSN
0040-4020

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## Abstract The selective Beckmann fragmentations of multifunctionalised ketoximes have been proven to proceed effectively to give the corresponding nitriles. The chiral (__E__)‐1,3,4‐tri‐__O__‐substituted‐6‐methoxy‐hex‐5‐en‐2‐one oxime derivatives, available from glycals and glycosyl glycals, gave