Newborn screening for phenylketonuria (PKU) began in the United States in the early 1960s following development of the Guthrie bacterial inhibition assay that allowed for the easy, rapid screening of elevated blood phenylalanine levels collected on newborn filter paper samples. Since that time, a nu
โฆ LIBER โฆ
The introduction of newborn screening for phenylketonuria
โ Scribed by R. Guthrie; H. Bickel
- Publisher
- Springer
- Year
- 1996
- Tongue
- English
- Weight
- 175 KB
- Volume
- 155
- Category
- Article
- ISSN
- 0340-6997
No coin nor oath required. For personal study only.
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## Abstract The aim of newborn screening is to identify presymptomatic healthy infants that will develop significant metabolic or endocrine derangements if left undiagnosed and untreated. The goal of ultimately reducing or eliminating irreversible sequelae is reached by maximizing test sensitivity
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