The intramolecular reductive coupling of 1,3-diphenyl-1,3-propanediol with titanium trichloride-lithium aluminum hydride. preparation of 1,2-diphenylcyclopropanes.
โ Scribed by A.L Baumstark; C.J McCloskey; T.J Tolson; G.T Syriopoulos
- Publisher
- Elsevier Science
- Year
- 1977
- Tongue
- French
- Weight
- 261 KB
- Volume
- 18
- Category
- Article
- ISSN
- 0040-4039
No coin nor oath required. For personal study only.
โฆ Synopsis
Titanium reagents have been shown to be effective in the intermolecular reductive coupling of carbonyls to olefins! Recently, several intramolecular coupling reactions of dicarbonyls
๐ SIMILAR VOLUMES
The intermolecular reductive coupling of carbonyls to olefins has been accomeliehed by a "umber of reagents1 of which the mst general is TiCL,-UAW+, Id,2 . MC Hurry swsted2, in 1974, the use of this reagent to couple 1,s and 1,6-diketones to form cyclic alefins. Recently, MC Murry and Fleming have s
cis\_ or tmns\_cinnamic acid (I and II, respectively) undergoes rearrangement to l, Z-diphenyl-2-propenol (III) during lithium aluminum hydride reduction. This claim was based on the following experimental results.