The intracerebroventriculary streptozotocin-treated rat: Impairment of cerebral glucose metabolism resembles the alterations of carbohydrate metabolism of the brain in Alzheimer's disease
β Scribed by R. Nitsch; G. Mayer; S. Hoyer
- Publisher
- Springer
- Year
- 1989
- Tongue
- English
- Weight
- 101 KB
- Volume
- 1
- Category
- Article
- ISSN
- 1435-1463
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C.H.), Federal Republic of Germany Intracerebroventricular (ICV) injection of streptozotocin (STZ) has been reported to impair cerebral glucose utilization and energy metabolism (Nitsch and Hoyer: Neurosci Lett, 128:199-202,1991) and also to prejudice passive avoidance learning in adult rats (Mayer
## Abstract Based upon data obtained with our arterioβvenous technique for the determination of cerebral metabolism in humans in vivo we have proposed a method for the determination of cerebral regional intermediary glucose metabolism in humans in vivo using specifically labeled ^11^Cβglucose and p