Involvement of the Golgi region in the i
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Madhusoodana P. Nambiar; Tatsuya Oda; Chaohua Chen; Yasuo Kuwazuru; Henry C. Wu
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Article
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1993
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John Wiley and Sons
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English
β 899 KB
The intracellular pathway following receptor-mediated endocytosis of cholera toxin was studied using brefeldin A (BFA), which inhibited protein secretion and induced dramatic morphological changes in the Golgi region. In both mouse Y1 adrcnal cells and CHO cells, BFA at 1 pgiml caused a 80-90% inhib