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The interleukin-2 receptor on malignant cells: A target for diagnosis and therapy

✍ Scribed by Thomas A. Waldmann

Book ID
113133590
Publisher
Elsevier Science
Year
1986
Tongue
English
Weight
640 KB
Volume
99
Category
Article
ISSN
0008-8749

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## Abstract DAB~486~IL‐2 is a genetically engineered fusion protein consisting of a portion of diphtheria toxin fused to human IL‐2. It is specifically cytotoxic for tumor cells which bear high‐affinity IL‐2 receptors (IL‐2R). DAB~389~IL‐2 is a similarly constructed hybrid protein which is smaller