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The Interleukin-12 Family: New Players in Transplantation Immunity?

✍ Scribed by S. Goriely; M. Goldman

Book ID
114804235
Publisher
John Wiley and Sons
Year
2007
Tongue
English
Weight
94 KB
Volume
7
Category
Article
ISSN
1600-6135

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πŸ“œ SIMILAR VOLUMES

THE INTERLEUKIN-12/INTERLEUKIN-12-RECEPT
THE INTERLEUKIN-12/INTERLEUKIN-12-RECEPTOR SYSTEM: Role in Normal and Pathologic Immune Responses
✍ Gately, Maurice K.; Renzetti, Louis M.; Magram, Jeanne; Stern, Alvin S.; Adorini πŸ“‚ Article πŸ“… 1998 πŸ› Annual Reviews 🌐 English βš– 258 KB

β–ͺ Abstract  Interleukin-12 (IL-12) is a heterodimeric cytokine that plays a central role in promoting type 1 T helper cell (Th1) responses and, hence, cell-mediated immunity. Its activities are mediated through a high-affinity receptor composed of two subunits, designated Ξ²1 and Ξ²2. Of these two sub