The interaction of tumour-localizing porphyrins with collagen, elastin, gelatin, fibrin and fibrinogen

Interaction of the fibrinogen-binding te

Interaction of the fibrinogen-binding tetrapeptide gly-pro-arg-pro with fine clots and oligomers of α-fibrin; comparison with αβ-fibrin

✍ Akira Shimizu; Günther Schindlauer; John D. Ferry 📂 Article 📅 1988 🏛 Wiley (John Wiley & Sons) 🌐 English ⚖ 828 KB

The tetrapeptide Gly-Pro-Arg-Pro(GPRP) was introduced by diffusion into fine unligated clots formed from human fibrinogen at pH 8.5 and ionic strength 0.45 by batroxobin (a-fibrin) and by thrombin (ap-fibrin). The a-fibrin clots were essentially liquefied a t GPRP concentrations above 1 m M and @-fi