The interaction of transition metal ions with DNA
β Scribed by N. Katsaros; A. Koutsodimou; E. Tselepi
- Publisher
- Elsevier Science
- Year
- 1989
- Tongue
- English
- Weight
- 74 KB
- Volume
- 36
- Category
- Article
- ISSN
- 0162-0134
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π SIMILAR VOLUMES
The polarographically determined binding constants of Cu++ and Cd++ to DNA were found to decrease with the degree of binding. The binding causes a reduction in the electrostatic potential $ on the DNA molecule. The binding constant conforms to the relation K = KO exp ( -z e $ / k T ) . The binding c
## Abstract New experimental data were obtained by means of circular dichroism, melting, renaturation, and kinetic experiments, upon Cu^2+^ binding to DNA, poly dAT, and poly dGdC. They enable us to propose a model of binding giving a satisfactory explanation to all of the data found in the literat
## Abstract The extent and modes of binding of the divalent metal ions Mn^2+^ and Co^2+^ to DNA and the effects of salt on the binding have been studied by measurements of the effects of these paramagnetic metal ions on the longitudinal and transverse relaxation rates of the protons of the solvent